Sermorelin vs Ipamorelin
Two growth-hormone-axis research peptides that act through different receptors.
Sermorelin and Ipamorelin both appear in growth-hormone research, but Sermorelin is a GHRH analog while Ipamorelin works through the ghrelin / GHS receptor.
Side-by-side
| Attribute | Sermorelin | Ipamorelin |
|---|---|---|
| Peptide class | GHRH analog (1-29 fragment) | Pentapeptide ghrelin-mimetic |
| Studied mechanism | GHRH-receptor stimulation of GH release | GHS-receptor stimulation of GH release |
| Duration note | Short-acting in research models | Short-acting, selective in research models |
| Common research context | GH-axis and aging models | GH-pulse and body-composition models |
| Often studied together | Sometimes paired to study dual pathways | Sometimes paired to study dual pathways |
Which does the research favor?
Sermorelin represents the GHRH side and Ipamorelin the ghrelin side of GH research — the choice depends on the receptor pathway under study.
Explore both compounds
Each ships with its Certificate of Analysis. Compare, then choose the compound that fits your research question.
For research use only. These products are intended solely for in-vitro laboratory research and are not for human or veterinary use. Nothing here is medical advice or a therapeutic claim.