MOTS-c
Mitochondrial-derived research peptide · Third-party COA on every batch
✓ Third-party verified purity · ✓ ISO/IEC 17025 accredited COA · ✓ US-shipped · ✓ Batch-tested
COA
Third-party Certificate of Analysis, every batch
17025
ISO/IEC accredited testing laboratory
USA
Domestic cold-chain fulfillment
Batch
Independently tested, every batch
Research Use Only. This article is for educational purposes. MOTS-c is intended solely for in-vitro laboratory research and is not for human or veterinary use.
MOTS-c has drawn significant research attention in cellular-metabolism and exercise-physiology studies. It is encoded within mitochondrial DNA — a feature that sets it apart from most research peptides.
What is MOTS-c?
MOTS-c (mitochondrial open reading frame of the twelve-S rRNA type-c) is a small peptide encoded within mitochondrial DNA. In research it is studied as a signaling molecule that communicates between the mitochondria and the rest of the cell, particularly around energy metabolism.
Studied mechanisms (in-vitro and preclinical)
In preclinical models, MOTS-c has been examined for its influence on the AMPK energy-sensing pathway and on glucose metabolism. Researchers study it in the context of metabolic regulation, insulin sensitivity, and exercise response.
MOTS-c and related research peptides
MOTS-c is often studied alongside other mitochondrial and metabolic tools such as SS-31, which targets the inner mitochondrial membrane, and NAD+, central to cellular energy. Together they let researchers probe different facets of mitochondrial function.
Quality and Certificate of Analysis
Every batch is analyzed by an independent, ISO/IEC 17025-accredited laboratory and ships with its own Certificate of Analysis documenting identity and purity. The COA is batch-specific and available on the product page.
Storage and handling
MOTS-c ships lyophilized. Store cold and out of light, reconstitute with bacteriostatic water, and keep the reconstituted vial refrigerated.
Frequently asked questions
What is MOTS-c used for in research?
It is studied as a mitochondrial-derived signaling peptide in metabolic and exercise-physiology research.
How does MOTS-c differ from SS-31?
MOTS-c is encoded in mitochondrial DNA and acts as a metabolic signal, while SS-31 is a targeted peptide that concentrates at the inner mitochondrial membrane.
Is MOTS-c approved for human use?
No. It is intended solely for in-vitro laboratory research and is not for human or veterinary use.
How should MOTS-c be stored?
Keep the lyophilized vial cold and out of light; once reconstituted, keep it refrigerated.
Go deeper on MOTS-c
For research use only. Not a drug, food, or supplement; not intended to diagnose, treat, cure, or prevent any disease; not for human or veterinary use.
